Heterozygous Pyrin (MEFV) E148Q allele carriers indicate a reduced glaucoma risk for Turkish population: a prospective clinical analysis

CONCLUSION: The pyrin variant of the MEFV gene resulting in a subclinical phenotype appears to reduce the incidence of glaucoma, and heterozygous pyrin (MEFV) E148Q allele carriers confer protection against glaucoma. It is important to consider the limitations arising from the relatively small number of studies conducted on this topic.PMID:38482581 | DOI:10.1080/13816810.2024.2324362

Source: Ophthalmic Genetics - March 14, 2024 Category: Opthalmology Authors: Orkun Muhsinoglu Ibrahim Akalin Remzi Karadag Sarenur Yilmaz Huseyin Bayramlar James D Nicholson Source Type: research