Validation of three-dimensional thoracic electrical impedance tomography of horses during normal and increased tidal volumes

Objective. Data from two-plane electrical impedance tomography (EIT) can be reconstructed into various slices of functional lung images, allowing for more complete visualisation and assessment of lung physiology in health and disease. The aim of this study was to confirm the ability of 3D EIT to visualise normal lung anatomy and physiology at rest and during increased ventilation (represented by rebreathing). Approach. Two-plane EIT data, using two electrode planes 20 cm apart, were collected in 20 standing sedate horses at baseline (resting) conditions, and during rebreathing. EIT data were reconstructed into 3D EIT whereby tidal impedance variation (TIV), ventilated area, and right-left and ventral-dorsal centres of ventilation (CoVRL and CoVVD, respectively) were calculated in cranial, middle and caudal slices of lung, from data collected using the two planes of electrodes. Main results. There was a significant interaction of time and slice for TIV (p

Source: Physiological Measurement - March 21, 2024 Category: Physiology Authors: David P Byrne, Nicole Studer, Cristy Secombe, Alexander Cieslewicz, Giselle Hosgood, Anthea Raisis, Andy Adler and Martina Mosing Source Type: research