Prevention of allergic reactions during oxaliplatin desensitization through inhibition of Bruton ’s tyrosine kinase

Capsule Summary: Acalabrutinib 100 mg orally twice daily starting in the evening 2 days before and continuing through a rapid drug desensitization protocol allowed a sensitized patient to successfully and safely receive oxaliplatin.

Source: Journal of Allergy and Clinical Immunology - March 21, 2024 Category: Allergy & Immunology Authors: Kristin A. Erickson, James E. Norton, Jennifer Law, Nicole Soriano, Malgorzata Strojny, Nicole Gentry, Morgan Fried, Bruce S. Bochner, Sheetal Kircher, Whitney W. Stevens Source Type: research