Developmental uterine anomalies in transgender patients receiving gender-affirming hysterectomies

Most developmental uterine anomalies occur due to Mullerian duct maldevelopment and are often incidentally discovered through pelvic imaging or intraoperatively. The incidence and prevalence of uterine anomalies are well known in the cisgender female general population. A few studies on gender-affirming hysterectomies have reported on the histological endometrial findings of patients using testosterone therapy, with findings of endometrial atrophy ranging from 18 to 50%. 1-3. However, there are no known studies which report developmental uterine anomalies in transgender male or nonbinary (TGNB) patients.

Source: American Journal of Obstetrics and Gynecology - March 21, 2024 Category: OBGYN Authors: N Nguyen, H Kim, M Sumida, R Galzote Source Type: research