CAR T cells and T cells phenotype and function are impacted by glucocorticoid exposure with different magnitude

Chimeric antigen receptor (CAR) T cell therapy is associated with high risk of adverse events. Glucocorticoids (GCs) are cornerstone in the management of high-grade cytokine release syndrome (CRS) and immune e...

Source: Journal of Translational Medicine - March 12, 2024 Category: Research Authors: Thomas Poiret, Sara Vikberg, Esther Schoutrop, Jonas Mattsson and Isabelle Magalhaes Tags: Research Source Type: research