Clinical Therapeutics for Proliferative Vitreoretinopathy in Retinal Detachment

Proliferative vitreoretinopathy (PVR) is an abnormal and prolonged healing response to retinal injury (retinal detachment, post-retinal detachment surgery) characterised by: pre/subretinal membrane formation; retinal gliosis and retinal shortening, retinal pigment epithelium cell proliferation; and increased glial (mainly Mu ¨ller cells), fibroblast and inflammatory cell (macrophage, lymphocyte) activity, leading to tractional retinal holes/breaks and multiple costly eye operations suffered by patients.

Source: Survey of Ophthalmology - March 14, 2024 Category: Opthalmology Authors: Francesco Sabatino, Philip Banerjee, Mahiul M. K. Muqit Tags: Review article Source Type: research