Future direction of total neoadjuvant therapy for locally advanced rectal cancer

Nature Reviews Gastroenterology & Hepatology, Published online: 14 March 2024; doi:10.1038/s41575-024-00900-9In this article, the authors discuss the use of total neoadjuvant therapy for locally advanced rectal cancer. They highlight ongoing trials and discuss future treatment options, including the potential use of multi-omics and artificial intelligence to facilitate treatment selection and prediction of response.

Source: Nature Reviews Gastroenterology and Hepatology - March 14, 2024 Category: Gastroenterology Authors: Yoshinori Kagawa J. Joshua Smith Emmanouil Fokas Jun Watanabe Andrea Cercek Florian R. Greten Hideaki Bando Qian Shi Julio Garcia-Aguilar Paul B. Romesser Natally Horvat Hanna Sanoff William Hall Takeshi Kato Claus R ödel Arvind Dasari Takayuki Yoshino Source Type: research