The role of G protein-coupled receptor kinases in GLP-1R β-arrestin recruitment and internalisation

This study advances mechanistic understanding of agonist-mediated GLP-1R internalisation and provides novel insights into how GRKs may fine-tune GLP-1R signalling.PMID:38461904 | DOI:10.1016/j.bcp.2024.116119

Source: Biochemical Pharmacology - March 10, 2024 Category: Drugs & Pharmacology Authors: Samantha M McNeill Jessica Lu Carlo Marion C Carino Asuka Inoue Peishen Zhao Patrick M Sexton Denise Wootten Source Type: research