Highlights on Fluorine-Containing Drugs Approved by U.S. FDA in 2023

Curr Top Med Chem. 2024 Mar 5. doi: 10.2174/0115680266300245240223070242. Online ahead of print.ABSTRACTFluorine continues to show its potential applications in drug discovery and development, as reflected by twelve drugs being fluorinated out of the fifty-five approved by the FDA in 2023. This concise review highlights the discovery of each of these fluorine-containing drugs in the past year, including its brand name, date of approval, composition, sponsors, indication, and mechanism of action. The relevant future trend is also briefly discussed.PMID:38445700 | DOI:10.2174/0115680266300245240223070242

Source: Current Topics in Medicinal Chemistry - March 6, 2024 Category: Chemistry Authors: Saghir Ali Andrew A Bolinger Jia Zhou Source Type: research