Effects of low-tube voltage coronary CT angiography on plaque and pericoronary fat assessment: intraindividual comparison

ConclusionLow tube voltages, particularly of 70 kV, have a significant effect on coronary plaque and FAI. The effect of low voltage on plaque composition is characterized by a polarization pattern, i.e., a decrease in fibrolipid (medium density) and an increase in necrotic core (low density) and calcification (high density).Clinical relevance statementOur results highlight the comparability and repeatability of plaque and pericoronary fat assessments facilitated by the same or a similar tube voltage. It is necessary to carry out studies on the specificity threshold of low tube voltage at each level.Key Points•Low tube voltage had a significant effect on coronary plaque and pericoronary fat, particularly 70 kV.•The effect of low tube voltage on plaque composition shows the shift from medium-density mixed components to low- and high-density components.•It is necessary to correct the specificity threshold or attenuation difference for low tube voltage at each level.Graphical Abstract
Source: European Radiology - Category: Radiology Source Type: research