Dose and dose rate dependence of the tissue sparing effect at ultra-high dose rate studied for proton and electron beams using the zebrafish embryo model

CONCLUSION: The ZFE model was shown to be a suitable pre-clinical high-throughput model for radiobiological studies on FLASH radiotherapy, providing results comparable to rodent models. This underlines the relevance of ZFE studies for FLASH radiotherapy research.PMID:38447870 | DOI:10.1016/j.radonc.2024.110197

Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - March 6, 2024 Category: Radiology Authors: Felix Horst Elisabeth Bodenstein Michael Brand Stefan Hans Leonhard Karsch Elisabeth Lessmann Steffen L öck Michael Sch ürer J örg Pawelke Elke Beyreuther Source Type: research