Older adults and non-response to rabies post-exposure prophylaxis: Challenges and approaches

We present a case of an 87-year-old male with rabies exposure who failed to respond to two series of RPEP with intramuscular rabies vaccination but responded to a third series using intradermal vaccine administration and provide reasoning for subsequent management. This case is brought forward to prompt discussion and research as to the utility of completing serology in older adults receiving RPEP as well as vaccination strategies, including route of administration, in those who do not respond to an initial course of RPEP vaccination.PMID:38444981 | PMC:PMC10914001 | DOI:10.14745/ccdr.v49i06a05
Source: Can Commun Dis Rep - Category: Infectious Diseases Authors: Source Type: research