A novel factor IXa-specific enzyme-linked immunosorbent assay detects factor IXa in human plasma

CONCLUSION: A monoclonal antibody was developed that specifically detects human FIXa protease. A FIXa-specific ELISA using the new antibody is capable of reproducibly measuring total FIXa in human plasma (both free FIXa and FIXa-antithrombin). This assay should facilitate the evaluation of total FIXa levels in a variety of clinical circumstances.PMID:38433974 | PMC:PMC10907220 | DOI:10.1016/j.rpth.2024.102338

Source: Thrombosis and Haemostasis - March 4, 2024 Category: Hematology Authors: Tina M Misenheimer Michael R Lasarev Kraig T Kumfer John P Sheehan Bradford S Schwartz Source Type: research