Unusual Enzymatic C-C Bond Formation and Cleavage Reactions during Natural Product Biosynthesis

Chem Pharm Bull (Tokyo). 2024;72(3):241-247. doi: 10.1248/cpb.c23-00889.ABSTRACTNatural products from plants and microorganisms provide a valuable reservoir of pharmaceutical compounds. C-C bond formation and cleavage are crucial events during natural product biosynthesis, playing pivotal roles in generating diverse and intricate chemical structures that are essential for biological functions. This review summarizes our recent findings regarding biosynthetic enzymes that catalyze unconventional C-C bond formation and cleavage reactions during natural product biosynthesis.PMID:38432903 | DOI:10.1248/cpb.c23-00889
Source: Chemical and Pharmaceutical Bulletin - Category: Drugs & Pharmacology Authors: Source Type: research