Formation and elimination of soluble fibrin and D-dimer in the bloodstream

In this study, we reviewed findings on the molecular mechanisms of the formation and dissolution of fibrin clots, fibrin-dependent activation of Glu-plasminogen by t-PA, and blood plasma behavior in the microcirculatory system. Finally, we proposed a model that explains the relations of D-dimer and soluble fibrin underlying the common and separate mechanisms of their formation and elimination.PMID:38168523 | PMC:PMC10797241 | DOI:10.3325/cmj.2023.64.421
Source: Croatian Medical Journal - Category: General Medicine Authors: Source Type: research