Fluidity of equipoise in a Multi-Centred Pilot RCT: Influences on clinician Decision-Making in offering trial entry

Second trimester miscarriage and very early preterm birth is a multifactorial complex condition [1]. Women often with no previous history or identifiable risk factors can present in emergency situations with cervical dilatation and exposed, unruptured foetal membranes in the peri-viable gestation period [1,2]. Management of premature cervical dilatation is complex and the evidence for interventions to prevent premature birth is limited; the placement of Emergency Cervical Cerclage (ECC) in attempt to keep the cervix closed is sometimes considered [2].
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - Category: OBGYN Authors: Tags: Full length article Source Type: research