Repeated Δ-9-Tetrahydrocannabinol administration dose dependently increases stablished schedule-induced drinking

ConclusionsThe present results show that repeated THC administration may (i) increase induced licking at moderate doses, (ii) reduce magazine entries, and (iii) affect the temporal pattern of SID. These findings suggest that THC does not appear to be beneficial to reduce compulsive behaviour in this animal model, while another collateral effect of THC —such as a greater habitual-like behaviour— needs to be considered.

Source: Psychopharmacology - February 28, 2024 Category: Psychiatry Source Type: research