An in vivo duck hepatitis B virus model recapitulates key aspects of nucleic acid polymer treatment outcomes in chronic hepatitis B patients

In conclusion, subcutaneous administration of NAPs in the DHBV duck model provides a useful tool for in vivo evaluation of NAPs. It recapitulates many aspects of this class of compound's efficacy in CHB patients, most notably the clear division between responders and non-responders.PMID:38401714 | DOI:10.1016/j.antiviral.2024.105835

Source: Antiviral Research - February 24, 2024 Category: Virology Authors: Yannick Debing Hannah Vanrusselt Lars Degrauwe Daniel Apol ônio Silva de Oliveira Christopher Kinyanjui Kariuki Ebanja Joseph Ebwanga Shahbaz Bashir Wouter Merckx Santhosh Kumar Thatikonda Vivek Rajwanshi Vikrant Gohil Jin Hong Dieudonn é Buh Kum Abel A Source Type: research