Vasoactive peptides as biomarkers for the prediction of retinopathy of prematurity

CONCLUSIONS: MR-proANP and CT-proET1 measured on day seven of life are strongly associated with ROP ≥ stage II in very preterm infants and might improve early prediction of ROP in the future.IMPACT: Plasma levels of midregional pro-atrial natriuretic peptide and C-terminal pro-endothelin-1 measured on day seven of life in very preterm infants show a strong association with development of retinopathy of prematurity ≥ stage II. Both biomarkers have the potential to improve early prediction of retinopathy of prematurity. Vasoactive peptides might allow to reduce the proportion of screened infants substantially.PMID:38402317 | DOI:10.1038/s41390-024-03091-w

Source: Pediatric Research - February 24, 2024 Category: Pediatrics Authors: Roland P Neumann Roland Gerull Pascal W Hasler Sven Wellmann Sven M Schulzke Source Type: research