Prostate-Specific Membrane Antigen PET/CT Detection of Prostate Cancer Metastasis to Thyroid and Cricoid Cartilages

Clin Nucl Med. 2024 Feb 23. doi: 10.1097/RLU.0000000000005111. Online ahead of print.ABSTRACTProstate-specific membrane antigen (PSMA) PET/CT has revolutionized the imaging of prostate cancer. Historically, prostate cancer metastasis to thyroid and cricoid cartilages was thought to be exceedingly rare, with only a few reported cases in the literature. Prostate cancer metastasis to the laryngeal cartilages was detected in 4 of 221 patients who underwent imaging with 18F-PSMA (Pylarify) or 68Ga-PSMA (Illuccix) PET/CT for initial staging of high-risk prostate cancer or restaging evaluation in the setting of biochemical recurrence from April 2022 through October 2023. The increased sensitivity and specificity of PSMA PET/CT allow for the detection of previously occult metastatic disease.PMID:38389203 | DOI:10.1097/RLU.0000000000005111
Source: Clinical Prostate Cancer - Category: Cancer & Oncology Authors: Source Type: research