KTN1 mediated unfolded protein response protects keratinocytes from ionizing radiation-induced DNA damage

The unfolded protein response (UPR) is one of the cytoprotective mechanisms against various stresses and essential for the normal function of skin. Skin injury caused by ionizing radiation (IR) is a common side effect of radiotherapy and it is unclear how UPR affects IR-induced skin injury.

Source: Journal of Dermatological Science - February 23, 2024 Category: Dermatology Authors: Xinli Niu, Yi Shen, Yunhan Wen, Xing Mi, Jing Xie, Ying Zhang, Zhenhua Ding Tags: Original Article Source Type: research