ST2-Mediated Neutrophilic Airway Inflammation: A Therapeutic Target for Patients With Uncontrolled Asthma

CONCLUSIONS: These results suggest that IL-33 induces the activation of neutrophils and Mϕ via ST2 receptors, leading to neutrophilic airway inflammation and poor control status of asthma. ST2 could be a therapeutic target for neutrophilic airway inflammation in patients with UA.PMID:38262389 | PMC:PMC10823144 | DOI:10.4168/aair.2024.16.1.22

Source: Allergy, Asthma and Immunology Research - January 23, 2024 Category: Allergy & Immunology Authors: Quang Luu Quoc Thi Bich Tra Cao Jae-Hyuk Jang Yoo Seob Shin Youngwoo Choi Hae-Sim Park Source Type: research