Factors Associated With Node-Positive Disease in Estrogen Receptor-Positive Breast Cancer Patients

Larger tumor size and shorter tumor-to-nipple distance at diagnosis are associated with greater risk of lymph node involvement in breast cancer. However, the relationship between receptor subtype status and lymph node metastasis remains unclear. Our objective  was to examine the association between primary tumor size, location, and nodal metastasis across estrogen receptor (ER)+/ progesterone receptor (PR)+/ human epidermal growth factor receptor 2 (HER2)-, ER+/PR-/HER2-, ER+/PR+/HER2+, and ER+/PR-/HER2+ tumors.

Source: Journal of Surgical Research - December 6, 2023 Category: Surgery Authors: Julia Gallagher, Kelly M. Elleson, Katherine Englander, Neha Chintapally, Weihong Sun, Junmin Whiting, Christine Laronga, Marie Catherine Lee Tags: Surgical Oncology Source Type: research