Impact of Increasing PD-L1 Levels on Outcomes to PD-1/PD-L1 Inhibition in Patients With NSCLC: A Pooled Analysis of 11 Prospective Clinical Trials

CONCLUSIONS: These analyses suggest PD-L1 expression has an appreciable impact on clinical outcomes for patients with NSCLC treated with ICI. As the impact of PD-L1 expression on outcomes may vary across regions, it is critical that future trials are multiregional and enroll a diverse patient population.PMID:38349736 | DOI:10.1093/oncolo/oyae006

Source: The Oncologist - February 13, 2024 Category: Cancer & Oncology Authors: Jonathon Vallejo Harpreet Singh Erin Larkins Nicole Drezner Biagio Ricciuti Pallavi Mishra-Kalyani Shenghui Tang Julia A Beaver Mark M Awad Source Type: research