CD36 regulates macrophage and endothelial cell activation and multinucleate giant cell formation in anti neutrophil cytoplasm antibody vasculitis

CONCLUSION: CD36 participates in macrophage and endothelial cell activation and MNGC formation, features of AAV pathogenesis. AAV treatment may involve targeting CD36 or MIF.PMID:38286173 | DOI:10.1016/j.clim.2024.109914

Source: Clinical Immunology - January 29, 2024 Category: Allergy & Immunology Authors: Xiang Zhang Catherine King Alexander Dowell Paul Moss Lorraine Harper Dimitrios Chanouzas Xiong-Zhong Ruan Alan David Salama Source Type: research