Optimizing cervical target volume in patients with nasopharyngeal cancer based on nodal drainage distance

CONCLUSIONS: In NPC, the maximum LN drainage distance was 3.95 cm without considering the direction. Specifically, in cranial-to-caudal direction, the sufficient vertical drainage distance was 2.81 cm, indicating that a 3-cm extension from the most inferior node may be rational as caudal border of the prophylactic clinical target volume (CTV). These findings promote in-depth understanding of nodal spreading patterns, uncovering paramount evidence for individualized CTV.PMID:38349999 | DOI:10.1158/1078-0432.CCR-23-3274

Source: Clinical Cancer Research - February 13, 2024 Category: Cancer & Oncology Authors: Yang Liu Wenbin Yan Chaosu Hu Xiaodong Huang Kai Wang Yuan Qu Xuesong Chen Runye Wu Ye Zhang Jianghu Zhang Jingwei Luo Ye-Xiong Li Jingbo Wang Junlin Yi Source Type: research