The individualized delineation of clinical target volume for primary nasopharyngeal carcinoma based on invasion risk of substructures: a prospective, real-word study with a large population

Nasopharyngeal carcinoma (NPC) is one of the most common malignancies in Southeast Asia, exhibiting a significantly uneven geographic distribution [1]. Radiotherapy is the backbone of treatment for NPC due to its inherent radiosensitivity and the intricate anatomic location of the tumor. Intensity modulated radiotherapy (IMRT) can deliver conformal and homogeneous dose distribution to the target area while spare surrounding normal tissue at the same time [2 –4]. A growing body of evidence has demonstrated the efficacy of IMRT in enhancing tumor local control rates and minimizing radiation-induced side effects, making it the primary radiotherapy technique for NPC [5,6].

Source: Radiotherapy and Oncology - February 14, 2024 Category: Radiology Authors: Xiaohui Wang, Nan Huang, Pui Lam Yip, Jing Wang, Runda Huang, Zhuang Sun, Dehua Kang, Qian He, Xiaowu Deng, Chong Zhao, Melvin L.K. Chua, Fei Han Tags: Original Article Source Type: research