Incorporating functional annotation with bilevel continuous shrinkage for polygenic risk prediction

Genetic variants can contribute differently to trait heritability by their functional categories, and recent studies have shown that incorporating functional annotation can improve the predictive performance o...

Source: BMC Bioinformatics - February 9, 2024 Category: Bioinformatics Authors: Yongwen Zhuang, Na Yeon Kim, Lars G. Fritsche, Bhramar Mukherjee and Seunggeun Lee Tags: Research Source Type: research