Short course radiotherapy versus radiochemotherapy for locally advanced rectal cancers in the elderly (UNICANCER PRODIGE 42 / GERICO 12 study) : quality of life and comprehensive geriatric assessment

Recent progress in the management of locally advanced rectal cancers with intensification of neoadjuvant strategies has improved local control [1], relapse-free survival [2,3] and even overall survival [4]. The corollary of these progressive intensifications has been an increase in side effects, which may have important consequences, in particular in fragile populations like the elderly [5]. 2-year mortality in the most fragile elderly patients exceeds 40% [6], and it amounts to 16-25% in the group of patients who are beginning to lose their autonomy and/or present co-morbidities [6].

Source: Radiotherapy and Oncology - February 8, 2024 Category: Radiology Authors: Eric Fran çois, Nicolas Magné, Rabia Boulahssass, Philippe Ronchin, Virginie Huguenet, Blandine De Lavigerie, Elodie Nouhaud, atherine Cattenoz, Isabelle Martel-Lafay, Catherine Terret, Pascal Artru, Pierre Clavere, Achille Tchalla, Veronique Vendrely, Tags: Original Article Source Type: research