Comprehensive multiscale analysis of lactate metabolic dynamics in vitro and in vivo using highly responsive biosensors

Nature Protocols, Published online: 02 February 2024; doi:10.1038/s41596-023-00948-yFiLa biosensors allow real-time subcellular analysis of lactate metabolism. This protocol describes their preparation and characterization, and their use in in vitro and in vivo assays, under various nutritional and pharmacological conditions.

Source: Nature Protocols - February 2, 2024 Category: Biomedical Science Authors: Aoxue Wang Yejun Zou Shuning Liu Xiuze Zhang Ting Li Lijuan Zhang Ruwen Wang Yale Xia Xie Li Zhuo Zhang Tiemin Liu Zhenyu Ju Ru Wang Joseph Loscalzo Yi Yang Yuzheng Zhao Source Type: research