Tenosynovial giant cell tumor: case report and molecular investigation

Tenosynovial giant cell tumor is a benign neoplasm arising from the synovium of joints, including the temporomandibular joint (TMJ). Despite its benign nature, these tumors may exhibit aggressive behavior. A 57-year-old woman with a swollen, hardened area in the left TMJ was referred to the University ´s clinic. The diagnosis of tenosynovial giant cell tumor was made based on the presence of hyperplastic synovial lining containing mononuclear and giant cells, hemorrhagic areas, hemosiderin deposits, and calcification foci in the biopsy.

Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - February 2, 2024 Category: ENT & OMF Authors: Let ícia Martins Guimarães, Victor Coutinho Bastos, Marina Rocha Fonseca Souza, Wagner Henriques de Castro, Carolina Cavaliéri Gomes, Ricardo Santiago Gomez Source Type: research