BORIS/CTCFL epigenetically reprograms clustered CTCF binding sites into alternative transcriptional start sites

Pervasive usage of alternative promoters leads to the deregulation of gene expression in carcinogenesis and may drive the emergence of new genes in spermatogenesis. However, little is known regarding the mecha...

Source: Genome Biology - January 31, 2024 Category: Genetics & Stem Cells Authors: Elena M. Pugacheva, Dharmendra Nath Bhatt, Samuel Rivero-Hinojosa, Md Tajmul, Liron Fedida, Emma Price, Yon Ji, Dmitri Loukinov, Alexander V. Strunnikov, Bing Ren and Victor V. Lobanenkov Tags: Research Source Type: research