New Hybrid Cytisine Derivatives Containing a Thienopyrimidine Fragment

New cytisine-thienopyrimidine hybrid molecules were synthesized by reacting cytisine with 4-chlorothieno [2,3-d]pyrimidines in the presence of Et3N. The solvent effect on the course of the reaction was studied. The structures of the obtained compounds were elucidated using IR,1H and13C NMR spectroscopy and TLC-MS spectrometry. X-ray crystal structure analyses of the synthesized compounds were performed.

Source: Chemistry of Natural Compounds - January 30, 2024 Category: Chemistry Source Type: research