Acute ketone supplementation in the absence of muscle glycogen utilization: Insights from McArdle disease

Ketone supplementation is gaining popularity. Yet, its effects on exercise performance when muscle glycogen cannot be used remain to be determined. McArdle disease can provide insight into this question, as these patients are unable to obtain energy from muscle glycogen, presenting a severely impaired physical capacity. We therefore aimed to assess the effects of acute ketone supplementation in the absence of muscle glycogen utilization (McArdle disease).

Source: Clinical Nutrition - January 25, 2024 Category: Nutrition Authors: Pedro L. Valenzuela, Alfredo Santalla, Lidia B. Alejo, Asunci ón Bustos, Laureano M. Ozcoidi, Laura Castellote-Bellés, Roser Ferrer-Costa, Mónica Villarreal-Salazar, María Morán, David Barranco-Gil, Tomás Pinós, Alejandro Lucia Tags: Original article Source Type: research