MIRO study: Do the results of a randomized controlled trial apply in a real population?

The aim of our study was to evaluate the external validity of the MIRO randomized controlled trial findings in a similar nationwide setting “real life” population, especially the benefit of a hybrid approach in esophageal resection for pulmonary complication. The external validity of randomized controlled trial findings to the general population with the same condition remains problematic because of the inherent selection bias and r igid inclusion criteria.

Source: Surgery - January 22, 2024 Category: Surgery Authors: Alexandre Challine, Mehdi Kirouani, Sheraz R. Markar, Stylianos Tzedakis, Romain Jaquet, Guillaume Piessen, Tienhan Sandrine Dabakoyo-Yonli, J érémie H. Lefèvre, Andrea Lazzati, Thibault Voron Source Type: research