PD-1 signaling uncovers a pathogenic subset of T cells in inflammatory arthritis

PD-1 is an immune checkpoint on T cells, and interventions to block this receptor result in T cell activation and enhanced immune response to tumors and pathogens. Reciprocally, despite a decade of research, a...

Source: Arthritis Research and Therapy - January 22, 2024 Category: Rheumatology Authors: Johanna Straube, Shoiab Bukhari, Shalom Lerrer, Robert J. Winchester, Yevgeniya Gartshteyn, Brian S. Henick, Matthew A. Dragovich and Adam Mor Tags: Research Source Type: research