DeepVelo: deep learning extends RNA velocity to multi-lineage systems with cell-specific kinetics

Existing RNA velocity estimation methods strongly rely on predefined dynamics and cell-agnostic constant transcriptional kinetic rates, assumptions often violated in complex and heterogeneous single-cell RNA s...

Source: Genome Biology - January 19, 2024 Category: Genetics & Stem Cells Authors: Haotian Cui, Hassaan Maan, Maria C. Vladoiu, Jiao Zhang, Michael D. Taylor and Bo Wang Tags: Method Source Type: research