A generalised method for calculating repopulation-corrected tumour EQD2 values in a wide range of clinical situations, including interrupted treatments

The use of EQD2 (equivalent dose in 2  Gy fractions) as an iso-effective descriptor of any radiotherapy treatment schedule is well-established [1]. The EQD2 metric allows, in principle at least, any schedule to be expressed in terms of the iso-effective total dose required if it were to be delivered using conventional 2 Gy fractionati on. Such an approach has been recommended as it is useful for clinicians seeking an appreciation of the likely effectiveness of relatively novel treatment patterns [2].
Source: Physica Medica: European Journal of Medical Physics - Category: General Medicine Authors: Source Type: research