The LINC01176-miR-218-5p-IL-36G Network is Responsible for the Pathogenesis of Psoriasis by Promoting Inflammation

CONCLUSION: Our study shows that LINC01176 promotes the proliferation and invasion of keratinocytes and inhibits apoptosis by targeting miR-218-5p, which acts as a repressor of the psoriasis-associated IL-36G. The shRNA-LINC01176 emulsion showed potential treatment capability in alleviating symptoms of psoriasis.PMID:38193028 | PMC:PMC10771785 | DOI:10.2147/CCID.S444265

Source: Clinical, Cosmetic and Investigational Dermatology - January 9, 2024 Category: Dermatology Authors: Zongfeng Zhao Jie Cheng Wanqun Sun Jian Zhu Sheng Lu Yanyan Feng Zhendong Song Yali Yang Xiujuan Wu Source Type: research