Dysregulation of extracellular matrix and Lysyl Oxidase in Ehlers-Danlos syndrome type IV skin fibroblasts

Ehlers-Danlos syndrome Type IV (aka Vascular Ehlers Danlos, or vEDS) is a dominantly inherited mutation in the Collagen 3A1 gene (COL3A1). The disease is characterized by tissue friability and age-related suscept...

Source: Orphanet Journal of Rare Diseases - January 5, 2024 Category: Internal Medicine Authors: Reece Foehr, Keith Anderson, Owen Dombrowski, Anna Foehr and Erik D. Foehr Tags: Research Source Type: research