Efficacy and safety of denosumab versus zoledronic acid in OI adults: A prospective, open-label, randomized study

CONCLUSION: Denosumab effectively increases aBMD in OI adults, with similar efficacy to zoledronic acid. Long-term and large-sample studies are needed to confirm the anti-fracture efficacy and safety of denosumab in adult OI patients.PMID:38181430 | DOI:10.1210/clinem/dgae012

Source: The Journal of Clinical Endocrinology and Metabolism - January 5, 2024 Category: Endocrinology Authors: Xiaoyun Lin Jing Hu Bingna Zhou Xiaojie Wang Qian Zhang Yan Jiang Ou Wang Weibo Xia Xiaoping Xing Mei Li Source Type: research