Evaluating Policies of Expanding vs. Restricting First-Line Treatment Choices: A Cost-Effectiveness Analysis Framework

Healthcare payers often implement coverage policies that restrict the utilization of costly new first-line treatments. Cost-effectiveness analysis (CEA) can be conducted to inform these decisions by comparing the new treatment to an existing one. However, this approach may overlook important factors such as treatment effect heterogeneity and endogenous treatment selection, policy implementation costs, and diverse patient preferences across multiple treatment options. We aimed to develop a comprehensive CEA framework that considers these real-world factors, facilitating the evaluation of alternative policies related to expanding or restricting first-line treatment choices.
Source: Value in Health - Category: International Medicine & Public Health Authors: Source Type: research