AZD1775 and anti-PD-1 antibody synergistically sensitize hepatoma to radiotherapy

CONCLUSIONS: This work suggests that AZD1775 and anti-PD-1 Ab synergistically sensitize hepatoma to radiotherapy by enhancing IR-induced DNA damage and improving cytotoxic CD8+ T cells in TME.PMID:38167245 | DOI:10.1097/CM9.0000000000002988

Source: Chinese Medical Journal - January 3, 2024 Category: General Medicine Authors: Yichun Yin Jian Wang Junxuan Yi Kaiyue Zhang Zimeng Yin Sunzi Jin Baisong Zheng Source Type: research