Characterisation of the pruritus responses and pruritic behaviours in an interleukin 31-induced canine model of pruritus

CONCLUSIONS AND CLINICAL RELEVANCE: In conclusion, intravenous IL-31 reproducibly induces itch responses in dogs. Future evaluations of the canine IL-31 pruritic model should assess total pruritic behaviours in seconds rather than using a biased 'YES/NO' behaviour per 1 min scoring system.PMID:38149639 | DOI:10.1111/vde.13231

Source: Veterinary Dermatology - December 27, 2023 Category: Veterinary Research Authors: Jason Pearson Tara Denley Amanda Blubaugh Sujung Jun Kim Jonathan E Fogle Renato Leon Caleb Goss Frane Banovic Source Type: research