Transcatheter Mitral Valve Replacement in Patients with Mitral Annular Calcification: A Review

Heart Int. 2023 Mar 29;17(1):19-26. doi: 10.17925/HI.2023.17.1.19. eCollection 2023.ABSTRACTMitral annular calcification (MAC) is a progressive degenerative calcification of the mitral valve (MV) that is associated with mitral stenosis, regurgitation or both. Patients with MAC are poor candidates for MV surgery because of technical challenges and high peri-operative mortality. Transcatheter MV replacement (TMVR) has emerged as an option for such high surgical risk patients. This has been described with the use of the SAPIEN transcatheter heart valve (valve-in-MAC) and dedicated TMVR devices. Careful anatomic assessment is important to avoid complications of TMVR, such as left ventricular outflow tract obstruction, valve migration, embolization and paravalvular mitral regurgitation. In this review, we discuss the pathology, importance of preprocedural multimodality imaging for optimal patient selection, clinical outcomes and complications associated with TMVR in patients with MAC.PMID:37456353 | PMC:PMC10339466 | DOI:10.17925/HI.2023.17.1.19
Source: Heart International - Category: Cardiology Authors: Source Type: research