A composite decision rule of CD8+ T cell density in tumor biopsies predicts efficacy in early-stage, immunotherapy trials

CONCLUSIONS: We propose that a composite score of CD8+ T cell density in paired biopsies taken before and on-treatment may be a new biomarker to inform on clinical outcomes in early immunotherapy clinical trials.PMID:38127293 | DOI:10.1158/1078-0432.CCR-23-1572

Source: Clinical Cancer Research - December 21, 2023 Category: Cancer & Oncology Authors: David Dejardin Anton Kraxner Annika Blank Natascha Rieder Volker Teichgr äber Nicolas St ädler Ulrich Beyer Bruno Gomes Jehad Charo Source Type: research