P50 Joint Modelling of Intermediate Longitudinal Biomarkers to Predict Overall Survival in Patients with Solid Tumors

Joint modelling (JM) of longitudinal and time-to-event data simultaneously can provide an estimated biomarker profile (adjusted for informative dropout due to death) or predictions of the time-to-event outcome conditional upon the longitudinal biomarker profile. This application explores the association between tumor burden and overall survival (OS) in patients with solid tumors, compared to a traditional parametric approach.
Source: Value in Health - Category: International Medicine & Public Health Authors: Source Type: research