Regarding the article entitled “Standards for the care of people with cystic fibrosis: A timely and accurate diagnosis”

We were very interested to read the paper by Castellani et  al., because it has presented a different point of view from the 2018 European Cystic Fibrosis Society best practice guidelines, which does not mention sweat conductivity [1]. Based on the metanalysis recently published by our team [2], the authors have stated that the “measurement of sweat cond uctivity is not sufficient as a single test to establish a CF diagnosis, but a normal result may be meaningful to exclude a CF diagnosis” [3].
Source: Journal of Cystic Fibrosis - Category: Respiratory Medicine Authors: Source Type: research