The emerging role of miR-320a in lung cancer: a comprehensive review

Biomark Med. 2023 Dec 14. doi: 10.2217/bmm-2023-0215. Online ahead of print.ABSTRACTA specialized biomarker(s) for lung cancer is imperative owing to its high mortality. Continuing our earlier work demonstrating the role of miR-320a as a tumor suppressor, here we discuss the most recent updates on miR-320a in lung cancer pathogenesis. We found that miR-320a modulates levels of diverse cancer-associated molecules and signaling pathways, and is also involved in modulating the immune microenvironment of lung cancer during its pathogenesis. We also discuss how miR-320a encapsulated in exosomes inhibits invasive phenotypes of lung cancer. Therefore, based on the multimodal role of miR-320a in lung cancer development and progression, we believe that miR-320a may be utilized as a potential diagnostic/prognostic marker and therapeutic target for lung cancer patients.PMID:38095986 | DOI:10.2217/bmm-2023-0215
Source: Future Medicine: Biomarkers in Medicine - Category: Internal Medicine Authors: Source Type: research