Journal club

Weaning strategies Weaning from mechanical ventilation (MV) is challenging period in the recovery from respiratory failure and weaning places a significant burden on healthcare resources. To date, standardised protocols on the best timing and specific steps for weaning from MV are lacking. Pham and colleagues conducted a multicentre (481 ICUs) prospective observational cohort study in 50 countries, named "WEAN SAFE" (Lancet Respir Med, 2023;11(5):465–476) to clarify current practises and outcomes of the weaning process in patients requiring invasive MV for at least 2 days. The most striking finding was that only 3817 (65.0%) out of 5869 enrolled patients were successfully weaned at day 90. The median time to achieve eligibility criteria for weaning (PEEP<10 cmH20, FiO2<0.5, no or low doses of vasopressors and no paralysing agents) to the first weaning attempt was 1 day (IQR 0–4). By contrast, there was a delay of 5 or more days in 1013 individuals...
Source: Thorax - Category: Respiratory Medicine Authors: Tags: Thorax Journal club Source Type: research